Microbiome Research, Transmission Studies & Environmental Studies
PI: Brendan Kelly, MD
Study Dates: 06/01/21 – 05/31/26
Funding Source: CDC
Area of Focus:
Healthcare-associated Infections; Microbiome Research; C. Diff;
Specific Aims: The projects proposed in this application seek to build on the strong foundation established by core and collaborative projects conducted by the Penn-CHOP investigators over the past 5 years.
PI: Ebbing Lautenbach, MD, MPH, MSCE
Study Dates: 7/1/20-8/31/22
Funding Source: CDC
Area of Focus:
ESBLS, transmission
Specific Aims: This project will answer key questions about the clinical and molecular determinants of transmission of community-onset ESBLs with a specific focus on transmission within the household.
PI: Ebb Lautenbach, MD, MSCE, MPH
Project Lead: Katie Chiotos
Study Dates: 6/1/2021-5/31/2026
Funding Source: Centers for Disease Control and Prevention
Area of Focus:
Respiratory microbiome, ventilator-associated pneumonia diagnostics, multidrug resistant organisms
Specific Aims:
Aim 1: To determine the longitudinal changes in LRT and GI alpha diversity attributable to antibiotic class exposure.
Aim 2: To determine the impact of LRT and GI dysbiosis on diagnosis of LRTI.
Aim 3: To determine the association between LRT and GI dysbiosis and MDRO and/or other bacterial colonization.
Study Dates: 06/01/23 – 12/31/25
Funding Source: CDC Prevention Epicenter Program
Area of Focus:
Environmental transmission of pathogens; healthcare-associated infection
Specific Aims:
This project aims to define high-touch objects and to determine effectiveness of cleaning within inpatient NEXUS areas including dialysis, radiology, and physical and occupational therapy
PI: Ebbing Lautenbach, MD, MPH, MSCE
Study Dates: 06/01/21 – 05/31/26
Funding Source: CDC
Area of Focus:
Healthcare-associated Infections; Microbiome Research; C. Diff;
Specific Aims: The projects proposed in this application seek to build on the strong foundation established by core and collaborative projects conducted by the Penn-CHOP investigators over the past 5 years.